Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532968 | 1.00 | KDM4C (0.48) | KDM4CRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL30227102 | 1.00 | KDM4C (0.48) | KDM4CRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL30776208 | 1.00 | KDM4C (0.48) | KDM4CRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL27870881 | 0.88 | HCRTR2 (0.42) | KDM4CALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL30521876 | 0.85 | BCAT2 (0.53) | KDM4CRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL19604229 | 0.85 | KDM4C (0.57) | KDM4CKDM4EALDH1A1ALOX15CYP3A4 | |
| SCHEMBL45147 | 0.85 | BCAT2 (0.53) | KDM4CRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL31227852 | 0.85 | BCAT2 (0.53) | KDM4CRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL28996120 | 0.84 | KDM4C (0.50) | KDM4CKDM4EHCAR2NAPRTALDH1A1 | |
| SCHEMBL29064572 | 0.83 | METAP2 (0.41) | KDM4CKDM4EALDH1A1ALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117597345-A | Heterocyclic derivatives as CaMKK2 inhibitors | 百时美施贵宝公司 | 2024-02-23 | — | — | CN | disclosed |