SCHEMBL30777918

SCHEMBL30777918

CC(C)(C)OC(=O)N1CCN(Cc2ccnc(N)c2)CC1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TBK1 Q9UHD2 20/20 0.62
IKBKE Q14164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18985904 1.00 TBK1 (0.62) TBK1IKBKE
SCHEMBL19004116 0.87 TBK1 (0.61) TBK1IKBKE
SCHEMBL1825509 0.86 TBK1 (0.53) TBK1
SCHEMBL18985740 0.82 TBK1 (0.47) TBK1
SCHEMBL19005099 0.82 TBK1 (0.53) TBK1
SCHEMBL19005101 0.82 TBK1 (0.53) TBK1
SCHEMBL1088443 0.82 GPR119 (0.59)
SCHEMBL1997213 0.82 MEN1 (0.49) TBK1
SCHEMBL30584532 0.82 MEN1 (0.49) TBK1
SCHEMBL12919953 0.82 TBK1 (0.57) TBK1IKBKE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117683020-A Aminopyridine compound of phthalazinone, preparation method thereof and application thereof in preparation of inhibitor and antitumor drug 华南理工大学 2024-03-12 CN disclosed