Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 18/20 | 0.61 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.50 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | CCNK | O75909 | 1/20 | 0.48 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1825509 | 0.87 | TBK1 (0.53) | TBK1CCNKCDK12 | |
| SCHEMBL30777918 | 0.87 | TBK1 (0.62) | TBK1IKBKE | |
| SCHEMBL18985904 | 0.87 | TBK1 (0.62) | TBK1IKBKE | |
| SCHEMBL1088443 | 0.83 | GPR119 (0.59) | — | |
| SCHEMBL12919953 | 0.83 | TBK1 (0.57) | TBK1IKBKE | |
| SCHEMBL31741032 | 0.82 | TBK1 (0.46) | TBK1WNT3A | |
| SCHEMBL15450908 | 0.82 | HRH3 (0.57) | TBK1WNT3A | |
| SCHEMBL4757117 | 0.82 | ALDH1A1 (0.46) | TBK1IKBKE | |
| SCHEMBL30520640 | 0.81 | MEN1 (0.50) | TBK1CCNKCDK12 | |
| SCHEMBL15265297 | 0.81 | TBK1 (0.57) | TBK1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102091-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | disclosed |