Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 9/20 | 0.49 |
| ▸ | GRM5 | P41594 | 8/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.48 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | QDPR | P09417 | 2/20 | 0.47 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.47 |
| ▸ | LIPC | P11150 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15157008 | 1.00 | NAMPT (0.56) | NAMPTPDK4GRM1GRM5CYP11B2 | |
| SCHEMBL31473896 | 0.91 | NAMPT (0.54) | NAMPTPDK4GRM1GRM5CYP11B2 | |
| SCHEMBL25238113 | 0.90 | NAMPT (0.53) | NAMPTPDK4GRM1GRM5CYP11B2 | |
| SCHEMBL15184378 | 0.90 | NAMPT (0.53) | NAMPTPDK4GRM1GRM5CYP11B2 | |
| SCHEMBL15174997 | 0.89 | NAMPT (0.53) | NAMPTPDK4GRM1GRM5CYP11B2 | |
| SCHEMBL31222913 | 0.89 | NAMPT (0.53) | NAMPTPDK4GRM1GRM5CYP11B2 | |
| SCHEMBL2954440 | 0.89 | QDPR (0.56) | NAMPTPDK4GRM1GRM5CYP11B2 | |
| SCHEMBL2908091 | 0.87 | NAMPT (0.60) | NAMPTPDK4GRM1GRM5CYP11B2 | |
| SCHEMBL29227506 | 0.87 | NAMPT (0.60) | NAMPTPDK4GRM1GRM5CYP11B2 | |
| SCHEMBL19940290 | 0.87 | NAMPT (0.53) | NAMPTPDK4GRM1GRM5CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460732-A | Pyrrolopyridone compounds, preparation method and application thereof | 杭州中美华东制药有限公司 | 2024-01-26 | — | — | CN | disclosed |