Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644649 | 1.00 | LMNA (0.60) | LMNAKCNMA1MEN1KMT2APOLB | |
| SCHEMBL30779586 | 0.85 | POLB (0.59) | LMNAMEN1KMT2APOLBHDAC1 | |
| SCHEMBL21644686 | 0.85 | POLB (0.59) | LMNAMEN1KMT2APOLBHDAC1 | |
| SCHEMBL21644546 | 0.74 | P2RX1 (0.56) | LMNAMEN1KMT2APOLBHDAC1 | |
| SCHEMBL21644559 | 0.73 | GAA (0.64) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL2605547 | 0.72 | KCNMA1 (0.64) | LMNAKCNMA1MEN1KMT2APOLB | |
| SCHEMBL20509055 | 0.70 | HSP90AA1 (0.43) | HDAC1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16335223 | 0.70 | MEN1 (0.79) | LMNAKCNMA1MEN1KMT2APOLB | |
| SCHEMBL21644533 | 0.69 | SMN1; SMN2 (0.53) | LMNAKCNMA1MEN1KMT2APOLB | |
| SCHEMBL30779608 | 0.69 | SMN1; SMN2 (0.53) | LMNAKCNMA1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111164074-B | Heat shock protein 90 inhibitors | 台北医学大学 | 2024-02-02 | — | — | CN | disclosed |