Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.67 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361096 | 1.00 | GPR35 (0.67) | GPR35SRD5A2SRD5A1KDM4EHPGD | |
| SCHEMBL6285596 | 0.94 | GPR35 (0.67) | GPR35SRD5A2SRD5A1KDM4EHPGD | |
| SCHEMBL29379466 | 0.94 | GPR35 (0.67) | GPR35SRD5A2SRD5A1KDM4EHPGD | |
| SCHEMBL335983 | 0.88 | SRD5A1 (0.70) | GPR35SRD5A2SRD5A1KDM4EHPGD | |
| SCHEMBL29217465 | 0.86 | XDH (0.48) | GPR35SRD5A2SRD5A1KDM4EHPGD | |
| SCHEMBL22129956 | 0.84 | GPR35 (0.63) | GPR35SRD5A2SRD5A1KDM4EHPGD | |
| SCHEMBL3100380 | 0.84 | SRD5A2 (0.58) | GPR35SRD5A2SRD5A1KDM4EHPGD | |
| SCHEMBL19506405 | 0.84 | GPR35 (0.67) | GPR35SRD5A2SRD5A1KDM4EHPGD | |
| SCHEMBL25721500 | 0.83 | GPR35 (0.61) | GPR35SRD5A2SRD5A1KDM4EHPGD | |
| SCHEMBL13173649 | 0.83 | SRD5A2 (0.56) | GPR35SRD5A2SRD5A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4406930-A1 | ISOTOPE-LABELLED INDOLE CARBOXYLIC ACID COMPOUND, MIXTURES AND ANALYTICAL METHOD THEREWITH | JEOL Ltd. (JP) | 2024-07-31 | — | — | EP | disclosed |
| CN-117800893-A | Indolecarboxylic acid compounds, mixtures of indolecarboxylic acid compounds, and analytical methods | 日本电子株式会社 | 2024-04-02 | — | — | CN | disclosed |