Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.67 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19506406 | 0.94 | GPR35 (0.67) | GPR35SMAD3KDM4EHPGDHSD17B10 | |
| SCHEMBL19506401 | 0.88 | GPR35 (0.58) | GPR35SMAD3KDM4EHPGDHSD17B10 | |
| SCHEMBL30779684 | 0.84 | GPR35 (0.67) | GPR35SMAD3KDM4EHPGDHSD17B10 | |
| SCHEMBL3361096 | 0.84 | GPR35 (0.67) | GPR35SMAD3KDM4EHPGDHSD17B10 | |
| SCHEMBL19506403 | 0.83 | XDH (0.46) | GPR35KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL22129956 | 0.81 | GPR35 (0.63) | GPR35SMAD3KDM4EHPGDHSD17B10 | |
| SCHEMBL49512 | 0.81 | GPR35 (1.00) | GPR35SMAD3KDM4EHPGDHSD17B10 | |
| SCHEMBL25721500 | 0.80 | GPR35 (0.61) | GPR35SMAD3KDM4EHPGDHSD17B10 | |
| SCHEMBL6285596 | 0.77 | GPR35 (0.67) | GPR35SMAD3KDM4EHPGDHSD17B10 | |
| SCHEMBL29379466 | 0.77 | GPR35 (0.67) | GPR35SMAD3KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017182340-A1 | USE OF O-GLYCOSYLATED INDOLE OR INDOLINE DERIVATIVE WITH GLYCOSIDASE FOR DEYING KERATIN FIBERS | L'OREAL (FR) | 2017-10-26 | — | — | WO | disclosed |