Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Akhdardiol SCHEMBL30780865 | 1.00 | HSD11B1 (0.49) | HSD11B1NR1H3HSD11B2LMNACYP3A4 | |
| Akhdardiol SCHEMBL31410949 | 1.00 | HSD11B1 (0.49) | HSD11B1NR1H3HSD11B2LMNACYP3A4 | |
| SCHEMBL26830219 | 0.83 | ALDH1A1 (0.42) | CYP3A4RXRARXRBRXRGPTPN1 | |
| SCHEMBL30018644 | 0.83 | ALDH1A1 (0.42) | CYP3A4RXRARXRBRXRGPTPN1 | |
| SCHEMBL30780864 | 0.83 | HSD11B1 (0.46) | HSD11B1NR1H3HSD11B2LMNACYP3A4 | |
| SCHEMBL146422 | 0.71 | HSD11B1 (0.45) | HSD11B1NR1H3HSD11B2LMNACYP3A4 | |
| SCHEMBL15588772 | 0.71 | HSD11B1 (0.45) | HSD11B1NR1H3HSD11B2LMNACYP3A4 | |
| SCHEMBL17507603 | 0.71 | IL1B (0.40) | LMNASMN1; SMN2BCHEACHENR1H4 | |
| SCHEMBL9883012 | 0.70 | ALDH1A1 (0.42) | CYP3A4ACHEPTPN1ALDH1A1 | |
| SCHEMBL22922221 | 0.69 | HSD11B1 (0.44) | HSD11B1NR1H3HSD11B2LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024038162-A1 | AKHDARDIOL FOR USE IN PREVENTING OR TREATING FUNGAL INFECTIONS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-02-22 | — | — | WO | claimed |
| WO-2024038162-A1 | AKHDARDIOL FOR USE IN PREVENTING OR TREATING FUNGAL INFECTIONS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-02-22 | — | — | WO | disclosed |
| WO-2024038162-A1 | AKHDARDIOL FOR USE IN PREVENTING OR TREATING FUNGAL INFECTIONS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-02-22 | — | — | WO | disclosed |
| WO-2024038162-A1 | AKHDARDIOL FOR USE IN PREVENTING OR TREATING FUNGAL INFECTIONS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-02-22 | — | — | WO | disclosed |