Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28933703 | 0.84 | TSHR (0.55) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL30780918 | 0.82 | TSHR (0.61) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL1413129 | 0.82 | TSHR (0.61) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| Bromide SCHEMBL28377987 | 0.80 | TSHR (0.50) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL11819373 | 0.79 | TSHR (0.57) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL14397069 | 0.79 | TSHR (0.57) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL8977870 | 0.78 | MAPT (0.53) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL12048735 | 0.77 | ABCG2 (0.59) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| Dinitrophenylene SCHEMBL27263366 | 0.77 | TSHR (0.81) | ALDH1A1KMT2ATSHRLMNAACHE | |
| SCHEMBL10651901 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327677-A1 | Mono-nitration of aromatic compounds | F. Hoffmann-La Roche AG (CH) | 2011-06-01 | — | — | EP | disclosed |
| EP-2016034-A2 | MONO-NITRATION OF AROMATIC COMPOUNDS | F. Hoffmann-Roche AG (CH) | 2009-01-21 | — | — | EP | disclosed |
| US-7429589-B2 | Mono-nitration of aromatic compounds via nitrate salts | HOFFMANN-LA ROCHE INC. (US) | 2008-09-30 | — | — | US | disclosed |
| WO-2007125034-A2 | MONO-NITRATION OF AROMATIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-11-08 | — | — | WO | disclosed |
| US-20070255057-A1 | Mono-nitration of aromatic compounds via nitrate salts | CEDILOTE MIALL | 2007-11-01 | — | — | US | disclosed |
| US-3931215-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070255057-A1 | Mono-nitration of aromatic compounds via nitrate salts | NOS2, NOS3, NOS1 | ALDH1A1 722/4885MAPT 1554/4885MEN1 2021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.