Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2590213 | 1.00 | HSD17B10 (0.67) | HSD17B10ALDH1A1HIF1AVCAM1RORC | |
| Fluoride SCHEMBL29135029 | 0.98 | HSD17B10 (0.64) | HSD17B10ALDH1A1HIF1AVCAM1RORC | |
| SCHEMBL29535654 | 0.83 | HSD17B10 (0.67) | HSD17B10ALDH1A1HIF1AVCAM1RORC | |
| SCHEMBL169304 | 0.83 | HSD17B10 (0.67) | HSD17B10ALDH1A1HIF1AVCAM1RORC | |
| SCHEMBL19654571 | 0.83 | HSD17B10 (0.67) | HSD17B10ALDH1A1HIF1AVCAM1RORC | |
| Ammonia Solution, Strong SCHEMBL28217171 | 0.82 | HSD17B10 (0.64) | HSD17B10ALDH1A1HIF1AVCAM1RORC | |
| SCHEMBL21835328 | 0.81 | HSPB1 (0.62) | HSD17B10ALDH1A1KMT2APDE7AMEN1 | |
| SCHEMBL85918 | 0.80 | HSD17B10 (1.00) | HSD17B10ALDH1A1VCAM1KMT2APDE7A | |
| SCHEMBL29360183 | 0.80 | HSD17B10 (1.00) | HSD17B10ALDH1A1VCAM1KMT2APDE7A | |
| SCHEMBL85604 | 0.80 | ALDH1A1 (0.69) | HSD17B10ALDH1A1HIF1AKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |