SCHEMBL169304

SCHEMBL169304

O=[N+]([O-])c1ccc(F)c(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.67
ALDH1A1 P00352 5/20 0.62
HIF1A Q16665 1/20 0.62
TDP1 Q9NUW8 2/20 0.53
KMT2A Q03164 3/20 0.53
MAPT P10636 3/20 0.51
MEN1 O00255 2/20 0.51
NPC1 O15118 1/20 0.51
MAPK1 P28482 1/20 0.51
RAB9A P51151 1/20 0.51
VCAM1 P19320 1/20 0.50
TDO2 P48775 1/20 0.50
HTT P42858 1/20 0.49
PDE7A Q13946 5/20 0.49
THRB P10828 1/20 0.47
RORC P51449 1/20 0.47
TSHR P16473 2/20 0.46
LMNA P02545 1/20 0.46
PDE4B Q07343 1/20 0.46
PDE4D Q08499 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19654571 1.00 HSD17B10 (0.67) HSD17B10ALDH1A1HIF1ATDP1KMT2A
SCHEMBL29535654 1.00 HSD17B10 (0.67) HSD17B10ALDH1A1HIF1ATDP1KMT2A
Ammonia Solution, Strong SCHEMBL28217171 0.98 HSD17B10 (0.64) HSD17B10ALDH1A1HIF1ATDP1KMT2A
SCHEMBL9484826 0.93 HSD17B10 (0.58) HSD17B10ALDH1A1HIF1ATDP1KMT2A
Alcohol SCHEMBL28117794 0.89 HSD17B10 (0.55) HSD17B10ALDH1A1HIF1ATDP1KMT2A
SCHEMBL27857909 0.84 ALDH1A1 (0.54) HSD17B10ALDH1A1HIF1ATDP1KMT2A
SCHEMBL30780972 0.83 HSD17B10 (0.67) HSD17B10ALDH1A1HIF1ATDP1KMT2A
SCHEMBL2590213 0.83 HSD17B10 (0.67) HSD17B10ALDH1A1HIF1ATDP1KMT2A
Fluoride SCHEMBL29135029 0.82 HSD17B10 (0.64) HSD17B10ALDH1A1HIF1ATDP1KMT2A
SCHEMBL1982719 0.81 HSPB1 (0.62) HSD17B10ALDH1A1HIF1AKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119972147-A Calcium carbonate/carbon composite carrier supported ruthenium catalyst, preparation method and application 郑州大学 2025-05-13 CN claimed
CN-119265602-A Preparation method and application of copper foam supported noble metal catalyst 重庆师范大学 2025-01-07 CN claimed
CN-113694936-B Copper-silver-gold nano alloy catalyst and preparation method and application thereof 江苏大学 2024-11-15 CN claimed
CN-118561694-A Method for continuously producing 3-chloro-4-fluoroaniline by adopting fixed bed reactor 浙江德力装备有限公司 2024-08-30 CN claimed
CN-118253327-A Nitrogen-doped carbon-loaded cobalt material and preparation method and application thereof 郑州大学 2024-06-28 CN claimed
CN-114805080-B Method for continuously separating 3-chloro-4-fluoronitrobenzene 福建技术师范学院 2024-06-14 CN claimed
CN-117800808-A Preparation method of 2, 4-dichloro fluorobenzene 帕潘纳(北京)科技有限公司 2024-04-02 CN claimed
CN-115453000-B Detection method and application of toxic impurities in tenib drug intermediate 广州艾格生物科技有限公司 2023-10-27 CN claimed
WO-2023174449-A1 METHOD FOR PREPARING N-(3-CHLORO-4-(2-PYRIDYLMETHOXY)PHENYL)-2-CYANOACETAMIDE 安庆朗坤药业有限公司 2023-09-21 WO claimed
CN-116539772-A Method for measuring chromatographic purity of 2, 4-dichlorobenzene and intermediate by HPLC method 云南云天化股份有限公司 2023-08-04 CN claimed
CN-1506348-A Production process of catalytically hydrogenating nitrobenzene halide to synthesize haloarylamine 浙江工业大学 2004-06-23 CN claimed
EP-0647472-B1 Composition of matter as Raney catalyst for hydrogenating halonitroaromatic compound and process using the same CENTRE NAT RECH SCIENT (FR) 2000-07-19 EP claimed
CN-1044899-C Synthetic process of 2,4-fluobenzene dichloride UNIV ZHEJIANG (CN) 1999-09-01 CN claimed
US-5689021-A NICKEL-ALUMINUM-MOLYBDENUM ALLOY CATALYST, FORMATION OF HALOGEN SUBSTITUTED ANILINES RHONE-POULENC CHIMIE (FR) 1997-11-18 US claimed
EP-0647472-A1 Composition of matter as Raney catalyst for hydrogenating halonitroaromatic compound and process using the same RHONE-POULENC CHIMIE (FR) 1995-04-12 EP claimed
EP-0307481-B1 PROCESS FOR PREPARING 3-CHLORO-4-FLUORONITROBENZENE NIPPON KAYAKU KK (JP) 1993-11-24 EP claimed
CN-1075949-A The 2,4 dichloro fluorobenzene synthesis technique NANJING MEDICINE INST (CN) 1993-09-08 CN claimed
CN-1070904-A The 2,4 dichloro fluorobenzene new process of production CHEMICAL GENERAL PLANT NO 2 JI (CN) 1993-04-14 CN claimed
US-4898996-A CHLORINATION WITH IODINE AND/OR IRON OR ANTIMONY COMPOUNDS AS CATALYSTS; BY-PRODUCT INHIBITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-02-06 US claimed
EP-0307481-A1 PROCESS FOR PREPARING 3-CHLORO-4-FLUORONITROBENZENE NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1989-03-22 EP claimed