Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20187737 | 0.80 | HTR2C (0.44) | HTR2CHTR2BPDE4B | |
| SCHEMBL19904536 | 0.79 | CSNK2A1 (0.64) | GLASMN1; SMN2CSNK2A1KMOPNMT | |
| SCHEMBL3718825 | 0.79 | HPGD (0.46) | CSNK2A1HTR2CHTR2BHPGDKMO | |
| SCHEMBL171697 | 0.79 | HPGD (0.46) | GLASMN1; SMN2CSNK2A1HTR2CHTR2B | |
| SCHEMBL1391511 | 0.79 | HPGD (0.51) | SMN1; SMN2CSNK2A1HTR2CHTR2BHPGD | |
| SCHEMBL9398865 | 0.78 | SMN1; SMN2 (0.47) | GLASMN1; SMN2CSNK2A1HPGD | |
| SCHEMBL18910042 | 0.78 | FFAR4 (0.58) | HPGDKMO | |
| SCHEMBL27339720 | 0.77 | HPGD (0.47) | CSNK2A1HTR2CHTR2BHPGDKMO | |
| SCHEMBL27341403 | 0.76 | HTR1A (0.45) | HTR2CHTR2BPDE4B | |
| SCHEMBL18910063 | 0.76 | KMO (0.46) | HPGDKMOPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |