Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.35 |
| ▸ | MME | P08473 | 3/20 | 0.34 |
| ▸ | CPA1 | P15085 | 3/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.34 |
| ▸ | ECE1 | P42892 | 4/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18921925 | 0.90 | ACE (0.35) | ACEMMECPA1ACE2ECE1 | |
| SCHEMBL30035137 | 0.89 | CTRB1 (0.34) | ACEMMECPA1ACE2 | |
| SCHEMBL25355936 | 0.89 | ACE (0.36) | ACEMMECPA1ACE2ECE1 | |
| SCHEMBL29973895 | 0.88 | PSMB1 (0.35) | — | |
| SCHEMBL30781089 | 0.88 | MME (0.41) | MMEECE1MMP2MMP7MMP9 | |
| SCHEMBL28515194 | 0.87 | ACE (0.36) | ACEMMECPA1ACE2ECE1 | |
| SCHEMBL20397512 | 0.87 | CTRB1 (0.33) | ACE | |
| SCHEMBL31064827 | 0.87 | BACE1 (0.35) | ACE | |
| SCHEMBL20397457 | 0.87 | CTRB1 (0.33) | ACE | |
| SCHEMBL29630389 | 0.87 | CTRB1 (0.33) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565325-A2 | FATTY ACID-D-AMINO ACID PEPTIDES CONJUGATES AS ANAPLEROTIC COMPOUNDS FOR USE IN TREATING PROPIONIC ACIDEMIA, METHYLMALONIC ACIDURIAS, AND ENERGY METABOLIC DISORDERS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2025-06-11 | — | — | EP | disclosed |
| CN-119855613-A | Fatty acid-D-amino acid peptide conjugates as anaplerotic compounds for the treatment of hyperuricemia, methylmalonic urine disorder and energy metabolism disorders | 匹兹堡大学高等教育联邦体系 | 2025-04-18 | — | — | CN | disclosed |
| WO-2024030367-A2 | FATTY ACID-D-AMINO ACID PEPTIDES CONJUGATES AS ANAPLEROTIC COMPOUNDS FOR USE IN TREATING PROPIONIC ACIDEMIA, METHYLMALONIC ACIDURIAS, AND ENERGY METABOLIC DISORDERS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2024-02-08 | — | — | WO | disclosed |