Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 4/20 | 0.35 |
| ▸ | CPA1 | P15085 | 3/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.35 |
| ▸ | ECE1 | P42892 | 3/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | GNPAT | O15228 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18921925 | 0.99 | ACE (0.35) | ACEALDH1A1MMECPA1ACE2 | |
| SCHEMBL20397511 | 0.90 | KDM4E (0.43) | ACEMMEECE1GNPAT | |
| SCHEMBL20397515 | 0.90 | KDM4E (0.43) | ACEMMEECE1GNPAT | |
| SCHEMBL6026424 | 0.89 | ALOX15 (0.42) | ALDH1A1TNFITGB3ITGA2BGNPAT | |
| SCHEMBL61370 | 0.89 | ALOX15 (0.42) | ALDH1A1TNFITGB3ITGA2BGNPAT | |
| SCHEMBL61371 | 0.89 | ALOX15 (0.42) | ALDH1A1TNFITGB3ITGA2BGNPAT | |
| SCHEMBL30781182 | 0.89 | ACE (0.35) | ACEMMECPA1ACE2ECE1 | |
| SCHEMBL28515194 | 0.88 | ACE (0.36) | ACEMMECPA1ACE2ECE1 | |
| SCHEMBL7162439 | 0.88 | ALOX15 (0.41) | ALDH1A1TNFITGB3ITGA2BGNPAT | |
| Water SCHEMBL8680771 | 0.88 | ALOX15 (0.41) | ALDH1A1TNFITGB3ITGA2BGNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139608-A1 | Synergistic Compositions For Enhancing TFEB-Mediated Intracellular Clearance | Celagenex Research (India) Pvt. Ltd. (IN) | 2023-07-27 | — | — | WO | disclosed |