Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30992316 | 0.93 | SIRT2 (0.38) | SIRT5SIRT2SIRT1SSTR3PTPN1 | |
| SCHEMBL30992310 | 0.93 | SIRT2 (0.38) | SIRT5SIRT2SIRT1SSTR3PTPN1 | |
| SCHEMBL23880502 | 0.91 | MAP1LC3B (0.37) | SIRT5TLR2MAP1LC3BSSTR3PTPN1 | |
| SCHEMBL19432556 | 0.91 | MAP1LC3B (0.37) | SIRT5TLR2MAP1LC3BSSTR3PTPN1 | |
| SCHEMBL23880537 | 0.91 | MAP1LC3B (0.37) | SIRT5TLR2MAP1LC3BSSTR3PTPN1 | |
| SCHEMBL31035944 | 0.91 | MAP1LC3B (0.37) | SIRT5TLR2MAP1LC3BSSTR3PTPN1 | |
| SCHEMBL27136824 | 0.89 | SSTR3 (0.37) | SIRT5SIRT2SIRT1MAP1LC3BSSTR3 | |
| SCHEMBL19731594 | 0.89 | MAP1LC3B (0.38) | SIRT5SIRT2SIRT1MAP1LC3BSSTR3 | |
| SCHEMBL15691954 | 0.88 | KMT2A (0.38) | SIRT5SIRT2SIRT1MAP1LC3BSSTR3 | |
| SCHEMBL30874648 | 0.88 | TLR2 (0.41) | SIRT5TLR2SIRT2SIRT1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4548937-A1 | ANTIBODY-DRUG COMPLEX | Eisai R&D Management Co., Ltd. (JP) | 2025-05-07 | — | — | EP | disclosed |
| US-20240148895-A1 | ANTIBODY-DRUG CONJUGATE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2024-05-09 | — | — | US | disclosed |
| WO-2024043319-A1 | ANTIBODY-DRUG COMPLEX | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2024-02-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240148895-A1 | ANTIBODY-DRUG CONJUGATE | ANTXR2, FCGR1A, HAX1 | SIRT5 3214/4885TLR2 1069/4885SIRT2 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.