Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL406534 | 0.80 | L3MBTL1 (0.67) | KMT2AMEN1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL3186980 | 0.74 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1POLBNPC1 | |
| SCHEMBL3187786 | 0.72 | L3MBTL1 (0.44) | KMT2AMEN1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL3211065 | 0.71 | NPC1 (0.54) | KMT2AGAAL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10938557 | 0.69 | ALDH1A1 (0.64) | ALDH1A1NPC1HPGDATM | |
| SCHEMBL3192244 | 0.69 | SMN1; SMN2 (0.73) | KMT2AMEN1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL31466812 | 0.68 | TRIP13 (0.61) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11817098 | 0.67 | APEX1 (0.53) | SMN1; SMN2ALDH1A1POLBNPC1HPGD | |
| SCHEMBL30423190 | 0.67 | APEX1 (0.53) | SMN1; SMN2ALDH1A1POLBNPC1HPGD | |
| SCHEMBL26105432 | 0.67 | TRIP13 (0.59) | KMT2AMEN1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12433868-B2 | Polymorphic forms of ST-246 and methods of preparation | SIGA TECHNOLOGIES, INC. (US) | 2025-10-07 | — | — | US | claimed |
| US-11890270-B2 | Polymorphic forms of ST-246 and methods of preparation | SIGA TECHNOLOGIES, INC. (US) | 2024-02-06 | — | — | US | claimed |