Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2795612 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTPKMKDM4EHPGD | |
| SCHEMBL2797897 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTPKMKDM4EHPGD | |
| SCHEMBL5040366 | 0.82 | KDM4E (0.68) | ALDH1A1MAPTPKMKDM4ERXFP1 | |
| SCHEMBL11999961 | 0.81 | KDM4E (0.74) | ALDH1A1MAPTPKMKDM4EHPGD | |
| SCHEMBL11389203 | 0.80 | ALDH1A1 (0.64) | ALDH1A1MAPTPKMKDM4EHPGD | |
| SCHEMBL17066941 | 0.78 | MEN1 (0.69) | ALDH1A1MAPTPKMKDM4EHPGD | |
| SCHEMBL30783436 | 0.78 | KCNA3 (0.61) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL30367071 | 0.78 | MEN1 (0.69) | ALDH1A1MAPTPKMKDM4EHPGD | |
| SCHEMBL11379787 | 0.78 | KCNA3 (0.61) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL9535544 | 0.77 | KDM4E (1.00) | ALDH1A1MAPTPKMKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120214990-A1 | QUINOLINONES AND QUINOXALINONES AS ANTIBACTERIAL COMPOSITION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214990-A1 | QUINOLINONES AND QUINOXALINONES AS ANTIBACTERIAL COMPOSITION | NQO2, ASNS, NDUFS1 | ALDH1A1 3142/4885MAPT 3361/4885PKM 3703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.