Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 10/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30784186 | 0.87 | METAP2 (0.38) | DDR1EGFRMETAP2CNR1TSHR | |
| SCHEMBL30721027 | 0.84 | DDR1 (0.42) | DDR1EGFRTSHRALDH1A1HTT | |
| SCHEMBL25360747 | 0.84 | DDR1 (0.42) | DDR1EGFRTSHRALDH1A1HTT | |
| SCHEMBL30784349 | 0.80 | DDR1 (0.38) | DDR1EGFRTSHRALDH1A1LMNA | |
| SCHEMBL30784327 | 0.79 | ALDH1A1 (0.47) | DDR1EGFRTSHRALDH1A1 | |
| SCHEMBL30783630 | 0.77 | METAP2 (0.39) | METAP2PIK3CALMNASMN1; SMN2 | |
| SCHEMBL30784012 | 0.77 | PDE1A (0.38) | DDR1EGFRPIK3CAHTT | |
| SCHEMBL30336004 | 0.76 | EGFR (0.43) | DDR1EGFRTSHRALDH1A1HTT | |
| SCHEMBL25360881 | 0.76 | EGFR (0.43) | DDR1EGFRTSHRALDH1A1HTT | |
| SCHEMBL30784459 | 0.73 | EGFR (0.40) | DDR1EGFRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |