Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336004 | 0.81 | EGFR (0.43) | EGFRF2RL3PRNPPPARGHTT | |
| SCHEMBL25360881 | 0.81 | EGFR (0.43) | EGFRF2RL3PRNPPPARGHTT | |
| SCHEMBL15228751 | 0.78 | ALDH1A1 (0.39) | HTTNPSR1L3MBTL1MEN1KMT2A | |
| SCHEMBL30784404 | 0.77 | EGFR (0.40) | EGFRF2RL3PRNPPPARGHTT | |
| SCHEMBL25360747 | 0.77 | DDR1 (0.42) | EGFRF2RL3PRNPPPARGHTT | |
| SCHEMBL30721027 | 0.77 | DDR1 (0.42) | EGFRF2RL3PRNPPPARGHTT | |
| SCHEMBL30721048 | 0.75 | EGFR (0.39) | EGFRF2RL3PRNPPPARGHTT | |
| SCHEMBL26957673 | 0.75 | EGFR (0.39) | EGFRF2RL3PRNPPPARGHTT | |
| SCHEMBL30784510 | 0.75 | PIK3CB (0.39) | EGFR | |
| SCHEMBL30784349 | 0.73 | DDR1 (0.38) | EGFRF2RL3PRNPPPARGHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |