Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | EED | O75530 | 2/20 | 0.37 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.37 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.37 |
| ▸ | AEBP2 | Q6ZN18 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650108 | 0.88 | L3MBTL1 (0.48) | KDM4EALDH1A1CYP1A2KMT2AHPGD | |
| SCHEMBL13753819 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL17434217 | 0.83 | HDAC1 (0.41) | KDM4EALDH1A1LMNACYP1A2MEN1 | |
| SCHEMBL11869160 | 0.82 | KDR (0.46) | KDM4EEEDRBBP4SUZ12AEBP2 | |
| SCHEMBL17238838 | 0.82 | CYP1A2 (0.55) | KDM4EALDH1A1LMNACYP1A2CYP2C19 | |
| SCHEMBL634151 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1PKMHPGDSMN1; SMN2 | |
| SCHEMBL14735049 | 0.81 | PIM1 (0.47) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1314957 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1LMNAKMT2APKM | |
| SCHEMBL30784382 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1LMNACYP1A2HPGD | |
| SCHEMBL3206636 | 0.77 | ALOX5 (0.46) | KDM4EEEDRBBP4SUZ12AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730977-A | Novel aryl heterocyclic compound, and preparation method and application thereof | 华东理工大学 | 2023-09-12 | — | — | CN | disclosed |