Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 4/20 | 0.43 |
| ▸ | IDO2 | Q6ZQW0 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30784308 | 0.86 | ATM (0.52) | SMN1; SMN2NPC1RAB9APIK3CDPIK3CB | |
| SCHEMBL30784114 | 0.78 | HTT (0.42) | SMN1; SMN2RAB9APIK3CDPIK3CBALDH1A1 | |
| SCHEMBL30783815 | 0.75 | ALDH1A1 (0.43) | SMN1; SMN2PIK3CDPIK3CBALDH1A1HSD17B10 | |
| SCHEMBL17537349 | 0.75 | KDM4E (0.64) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL30783853 | 0.74 | HTT (0.39) | TRPV4SMN1; SMN2RAB9AALDH1A1HSD17B10 | |
| SCHEMBL30784396 | 0.74 | HTT (0.39) | SMN1; SMN2RAB9APIK3CDPIK3CBALDH1A1 | |
| SCHEMBL30783830 | 0.74 | HTT (0.39) | SMN1; SMN2RAB9APIK3CDPIK3CBALDH1A1 | |
| SCHEMBL31427755 | 0.73 | POLB (0.47) | TRPV4SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL30784067 | 0.73 | HTT (0.39) | TRPV4SMN1; SMN2RAB9APIK3CDPIK3CB | |
| SCHEMBL9919072 | 0.73 | POLB (0.55) | GLATDO2IDO2IDO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |