Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 8/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30784051 | 0.84 | HTT (0.43) | PIK3CBCRHR1EGFR | |
| SCHEMBL30783689 | 0.84 | PIK3CB (0.39) | PIK3CB | |
| SCHEMBL30783887 | 0.83 | ALDH1A1 (0.39) | PIK3CB | |
| SCHEMBL30784279 | 0.81 | PIM1 (0.42) | PIK3CBKCNH2FLT3PIM1 | |
| SCHEMBL30783616 | 0.81 | HTT (0.38) | PIK3CBCRHR1EGFR | |
| SCHEMBL30784048 | 0.81 | CRHR1 (0.41) | PIK3CBCRHR1EGFR | |
| SCHEMBL30784377 | 0.81 | CCNC (0.45) | KCNH2 | |
| SCHEMBL30784031 | 0.79 | CCNC (0.44) | PIK3CBKCNH2 | |
| SCHEMBL30783875 | 0.79 | ALDH1A1 (0.39) | PIK3CB | |
| SCHEMBL30783630 | 0.78 | METAP2 (0.39) | PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |