Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27158244 | 1.00 | HDAC4 (0.41) | HDAC4HDAC6GPR119TRPV1APLNR | |
| SCHEMBL2675233 | 0.86 | GPR119 (0.42) | HDAC4HDAC6GPR119TRPV1USP30 | |
| SCHEMBL29202347 | 0.84 | USP30 (0.44) | HDAC4HDAC6GPR119USP30HPGDS | |
| SCHEMBL27158505 | 0.84 | USP30 (0.44) | HDAC4HDAC6GPR119USP30HPGDS | |
| SCHEMBL2675452 | 0.83 | GPR119 (0.41) | GPR119USP30POLBRBP4 | |
| SCHEMBL30785499 | 0.81 | RBP4 (0.53) | GPR119FNTAFNTBRBP4 | |
| SCHEMBL29202348 | 0.81 | RBP4 (0.53) | GPR119FNTAFNTBRBP4 | |
| SCHEMBL30785481 | 0.81 | RBP4 (0.53) | GPR119FNTAFNTBRBP4 | |
| SCHEMBL27157998 | 0.81 | RBP4 (0.53) | GPR119FNTAFNTBRBP4 | |
| SCHEMBL13400337 | 0.78 | MAPT (0.49) | HDAC4HDAC6GPR119TRPV1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642404-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-01 | — | — | CN | disclosed |