SCHEMBL30786116

SCHEMBL30786116

Nc1ccc2c(/C=C/c3ccc(CN4CCCC4)cn3)nn(C3CCCCO3)c2c1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PRKCQ Q04759 3/20 0.33
PRKCD Q05655 3/20 0.33
PDE1B Q01064 4/20 0.32
RET P07949 1/20 0.32
ACHE P22303 2/20 0.30
CHEK1 O14757 1/20 0.30
CDK4 P11802 1/20 0.30
CDK6 Q00534 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30786199 0.90 CYP4F2 (0.35) RXRARXRBRXRGPRKCQPRKCD
SCHEMBL30786118 0.88 PRKCQ (0.34) RXRARXRBRXRGPRKCQPRKCD
SCHEMBL30786142 0.85 RET (0.33) RXRARXRBRXRGRET
SCHEMBL30786167 0.81 PSEN1 (0.36) RXRARXRBRXRG
SCHEMBL31475223 0.81 FAAH (0.34) RXRARXRBRXRGPRKCQPRKCD
SCHEMBL4053570 0.80 RET (0.37) RETCHEK1
SCHEMBL4053575 0.80 RET (0.37) RETCHEK1
SCHEMBL30786196 0.79 KDR (0.43) RET
SCHEMBL31517065 0.79 FAAH (0.37) ALDH1A1PRKCQPRKCD
SCHEMBL31517057 0.79 KDM4E (0.34) PDE1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049071-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF BEYANG THERAPEUTICS CO LTD (CN) 2026-02-19 US disclosed
EP-4556466-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF Beyang Therapeutics Co., Ltd. (CN) 2025-05-21 EP disclosed
WO-2025082316-A1 OPHTHALMIC FORMATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 苏州必扬医药科技有限公司 2025-04-24 WO disclosed
CN-119604488-A Protein tyrosine kinase inhibitor and medical application thereof 苏州必扬医药科技有限公司 2025-03-11 CN disclosed
WO-2024032584-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF 苏州必扬医药科技有限公司 2024-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049071-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF KDR, FLT1, ERBB2 RXRA 3769/4885RXRB 2615/4885RXRG 3436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.