Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 3/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786116 | 0.88 | RXRA (0.33) | PRKCQPRKCDACHERXRARXRB | |
| SCHEMBL30786199 | 0.88 | CYP4F2 (0.35) | PRKCQPRKCDRXRARXRBRXRG | |
| SCHEMBL30786077 | 0.84 | RXRA (0.32) | RXRARXRBRXRG | |
| SCHEMBL30786167 | 0.82 | PSEN1 (0.36) | RXRARXRBRXRGHRH3 | |
| SCHEMBL31475223 | 0.82 | FAAH (0.34) | PRKCQPRKCDRXRARXRBRXRG | |
| SCHEMBL30786228 | 0.81 | PDCD1 (0.37) | PRKCQPRKCDACHEPDCD1CD274 | |
| SCHEMBL31517065 | 0.80 | FAAH (0.37) | PRKCQPRKCDKDR | |
| SCHEMBL30786196 | 0.80 | KDR (0.43) | KDR | |
| SCHEMBL31517057 | 0.80 | KDM4E (0.34) | PDE1B | |
| SCHEMBL29705188 | 0.80 | FGFR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |