SCHEMBL30786199

SCHEMBL30786199

Ic1ccc2c(/C=C/c3ccc(CN4CCCC4)cn3)nn(C3CCCCO3)c2c1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
PRKCQ Q04759 3/20 0.33
PRKCD Q05655 3/20 0.33
PDE1B Q01064 4/20 0.32
CDK4 P11802 2/20 0.31
CCND1 P24385 1/20 0.31
CDK2 P24941 1/20 0.31
PDE2A O00408 1/20 0.30
RET P07949 1/20 0.30
CDK6 Q00534 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30786116 0.90 RXRA (0.33) RXRARXRBRXRGPRKCQPRKCD
SCHEMBL30786118 0.88 PRKCQ (0.34) RXRARXRBRXRGPRKCQPRKCD
SCHEMBL30786244 0.85 CYP4F2 (0.34) CYP4F2CYP4A11RXRARXRBRXRG
SCHEMBL31475213 0.83 CYP4F2 (0.33) CYP4F2CYP4A11RXRARXRBRXRG
SCHEMBL31475221 0.83 PRKCQ (0.34) CYP4F2CYP4A11PRKCQPRKCDCDK4
SCHEMBL31475223 0.81 FAAH (0.34) RXRARXRBRXRGPRKCQPRKCD
SCHEMBL30786167 0.81 PSEN1 (0.36) CYP4F2CYP4A11RXRARXRBRXRG
SCHEMBL4905166 0.80 CYP4F2 (0.37) CYP4F2CYP4A11RET
SCHEMBL30388040 0.80 CYP4F2 (0.37) CYP4F2CYP4A11RET
SCHEMBL30236077 0.80 CYP4F2 (0.37) CYP4F2CYP4A11RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049071-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF BEYANG THERAPEUTICS CO LTD (CN) 2026-02-19 US disclosed
EP-4556466-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF Beyang Therapeutics Co., Ltd. (CN) 2025-05-21 EP disclosed
WO-2025082316-A1 OPHTHALMIC FORMATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 苏州必扬医药科技有限公司 2025-04-24 WO disclosed
CN-119604488-A Protein tyrosine kinase inhibitor and medical application thereof 苏州必扬医药科技有限公司 2025-03-11 CN disclosed
WO-2024032584-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF 苏州必扬医药科技有限公司 2024-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049071-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF KDR, FLT1, ERBB2 CYP4F2 4637/4885CYP4A11 3483/4885RXRA 3769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.