Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.34 |
| ▸ | HTR2A | P28223 | 8/20 | 0.34 |
| ▸ | HTR1A | P08908 | 4/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 2/20 | 0.30 |
| ▸ | AURKA | O14965 | 2/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.30 |
| ▸ | PAK4 | O96013 | 2/20 | 0.30 |
| ▸ | ABL1 | P00519 | 2/20 | 0.30 |
| ▸ | LCK | P06239 | 2/20 | 0.30 |
| ▸ | CSF1R | P07333 | 2/20 | 0.30 |
| ▸ | RET | P07949 | 2/20 | 0.30 |
| ▸ | MET | P08581 | 2/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.30 |
| ▸ | KIT | P10721 | 2/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31475173 | 0.93 | HTR2A (0.35) | DRD2HTR2AHTR1AAXLKDR | |
| SCHEMBL30786082 | 0.89 | DRD2 (0.35) | DRD2HTR2AHTR1A | |
| SCHEMBL31475169 | 0.86 | CNR1 (0.34) | PLK4AURKAMAP4K4PAK4ABL1 | |
| SCHEMBL31475199 | 0.85 | KDR (0.34) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL30786126 | 0.83 | DRD2 (0.32) | DRD2HTR2AHTR1AAXLMERTK | |
| SCHEMBL31475194 | 0.80 | KDR (0.34) | PLK4AURKAMAP4K4PAK4ABL1 | |
| SCHEMBL31475185 | 0.80 | KDR (0.34) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL31475210 | 0.80 | DRD2 (0.37) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL30786134 | 0.79 | KDR (0.38) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL30786236 | 0.79 | KDR (0.37) | DRD2HTR2AHTR1AKDRBMPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |