Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31475169 | 0.90 | CNR1 (0.34) | CNR1CNR2SMYD2AXLMERTK | |
| SCHEMBL30786082 | 0.89 | DRD2 (0.35) | DRD2HTR2ACNR1CNR2HTR1A | |
| SCHEMBL31475216 | 0.86 | DRD2 (0.33) | DRD2HTR2AHTR1A | |
| SCHEMBL30786128 | 0.86 | CNR1 (0.31) | CNR1CNR2 | |
| SCHEMBL30786158 | 0.83 | DRD2 (0.34) | DRD2HTR2AAXLMERTKHTR1A | |
| SCHEMBL31475173 | 0.81 | HTR2A (0.35) | DRD2HTR2ACNR1CNR2AXL | |
| SCHEMBL30786218 | 0.81 | KDR (0.31) | — | |
| SCHEMBL30786135 | 0.79 | KDR (0.35) | CNR1CNR2 | |
| SCHEMBL30786231 | 0.79 | DGAT2 (0.35) | CNR1CNR2AXLTYRO3MERTK | |
| SCHEMBL30786078 | 0.78 | KDR (0.36) | DRD2HTR2ACNR1CNR2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |