Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1875813 | 0.80 | HRH3 (0.54) | HTR3A | |
| SCHEMBL31475222 | 0.75 | FGFR1 (0.42) | LTA4HCCNE1CDK2CCNT1CDK9 | |
| SCHEMBL22171170 | 0.72 | CHRNB2 (0.52) | LTA4HCHRNB2CHRNA4PTGS2PSMB1 | |
| SCHEMBL22171116 | 0.71 | PSMB1 (0.51) | LTA4HCHRNB2CHRNA4PSMB1PSMB5 | |
| SCHEMBL23405928 | 0.69 | LTA4H (0.65) | LTA4HCHRNB2CHRNA4PTGS2PSMB1 | |
| SCHEMBL29743978 | 0.69 | LTA4H (0.65) | LTA4HCHRNB2CHRNA4PTGS2PSMB1 | |
| SCHEMBL20255227 | 0.69 | CHRNB2 (0.59) | LTA4HCHRNB2CHRNA4PTGS2PSMB1 | |
| SCHEMBL2328227 | 0.69 | LTA4H (0.60) | LTA4HCHRNB2CHRNA4PTGS2PSMB1 | |
| SCHEMBL31329166 | 0.69 | LTA4H (0.60) | LTA4HCHRNB2CHRNA4PTGS2PSMB1 | |
| SCHEMBL18291218 | 0.69 | LTA4H (0.60) | LTA4HCHRNB2CHRNA4PTGS2PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |