Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 5/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.33 |
| ▸ | PLK4 | O00444 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | PAK4 | O96013 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786236 | 0.93 | KDR (0.37) | KDRDRD4MEN1KMT2ACNR1 | |
| SCHEMBL31475235 | 0.92 | KDR (0.46) | KDRDRD4MEN1KMT2ACNR1 | |
| SCHEMBL30786135 | 0.91 | KDR (0.35) | KDRDRD4MEN1KMT2ACNR1 | |
| SCHEMBL30786076 | 0.88 | KDR (0.47) | KDRDRD4MEN1KMT2ACNR1 | |
| SCHEMBL30786156 | 0.87 | KDR (0.35) | KDRDRD4MEN1KMT2ACNR1 | |
| SCHEMBL31475279 | 0.86 | KDR (0.48) | KDRDRD4MEN1KMT2ACNR1 | |
| SCHEMBL30786208 | 0.85 | KDR (0.38) | KDRCNR1CNR2 | |
| SCHEMBL30786075 | 0.83 | KDR (0.49) | KDRDRD4FGFR1PLK4AURKA | |
| SCHEMBL30786232 | 0.82 | KDR (0.66) | KDRDRD4FGFR1PLK4AURKA | |
| SCHEMBL30786134 | 0.81 | KDR (0.38) | KDRCNR1CNR2BMPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |