Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 6/20 | 0.31 |
| ▸ | CNR2 | P34972 | 6/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.30 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786156 | 0.96 | KDR (0.35) | KDRDRD4MEN1KMT2ACNR1 | |
| SCHEMBL30786190 | 0.91 | KDR (0.44) | KDRDRD4MEN1KMT2ACNR1 | |
| SCHEMBL30786236 | 0.90 | KDR (0.37) | KDRDRD4MEN1KMT2ACNR1 | |
| SCHEMBL30786078 | 0.89 | KDR (0.36) | KDRDRD4CNR1CNR2BMPR1B | |
| SCHEMBL30786128 | 0.89 | CNR1 (0.31) | CNR1CNR2 | |
| SCHEMBL30786153 | 0.86 | KDR (0.36) | KDRDRD4KMT2A | |
| SCHEMBL31475235 | 0.85 | KDR (0.46) | KDRDRD4MEN1KMT2ACNR1 | |
| SCHEMBL30786208 | 0.84 | KDR (0.38) | KDRCNR1CNR2 | |
| SCHEMBL31475216 | 0.82 | DRD2 (0.33) | KDR | |
| SCHEMBL30786152 | 0.80 | KDR (0.35) | KDRCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025082316-A1 | OPHTHALMIC FORMATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州必扬医药科技有限公司 | 2025-04-24 | — | — | WO | disclosed |
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |