Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 6/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 4/20 | 0.31 |
| ▸ | CNR2 | P34972 | 4/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786236 | 0.93 | KDR (0.37) | KDRLMNACNR1CNR2 | |
| SCHEMBL31475235 | 0.92 | KDR (0.46) | KDRCNR1CNR2 | |
| SCHEMBL30786061 | 0.89 | KDR (0.38) | KDRCCR3MCHR1KCNH2CNR1 | |
| SCHEMBL31475160 | 0.88 | KDR (0.40) | KDRACKR3CCR3MCHR1KCNH2 | |
| SCHEMBL30786190 | 0.85 | KDR (0.44) | KDRCNR1CNR2 | |
| SCHEMBL30786156 | 0.85 | KDR (0.35) | KDRCCR3CNR1CNR2 | |
| SCHEMBL30786099 | 0.84 | KDR (0.39) | KDRMCHR1CNR1CNR2PDE4B | |
| SCHEMBL30786135 | 0.84 | KDR (0.35) | KDRCNR1CNR2 | |
| SCHEMBL30786134 | 0.83 | KDR (0.38) | KDRMCHR1KCNH2CNR1CNR2 | |
| SCHEMBL31475173 | 0.83 | HTR2A (0.35) | KDRCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |