SCHEMBL30786259

SCHEMBL30786259

Brc1ccn(CCCN2CCCC2)n1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
HRH3 Q9Y5N1 8/20 0.38
HRH4 Q9H3N8 2/20 0.38
SIGMAR1 Q99720 2/20 0.38
TDP1 Q9NUW8 1/20 0.36
LTA4H P09960 1/20 0.36
HRH1 P35367 1/20 0.36
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6308796 0.79 EHMT2 (0.39) L3MBTL1HRH3HRH4SIGMAR1TDP1
SCHEMBL6302511 0.78 HRH3 (0.41) HRH3HRH4SIGMAR1HRH1CYP1A2
SCHEMBL28811813 0.76 NR5A2 (0.45) SIGMAR1LMNAALDH1A1
SCHEMBL6305135 0.76 ALDH1A1 (0.38) L3MBTL1HRH3HRH4SIGMAR1TDP1
SCHEMBL30786164 0.76 HRH3 (0.39) HRH3HRH4SIGMAR1LTA4HHRH1
SCHEMBL31637679 0.74 CSNK2A2 (0.41)
SCHEMBL6308791 0.73 PARP1 (0.41) L3MBTL1HRH3HRH4SMN1; SMN2CYP1A2
SCHEMBL165242 0.72 PARP1 (0.43) L3MBTL1HRH3HRH4LMNASMN1; SMN2
SCHEMBL15412963 0.72 PKM (0.58) HRH3TDP1LMNACYP1A2CYP3A4
SCHEMBL6305129 0.70 PARP1 (0.38) L3MBTL1HRH3HRH4TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049071-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF BEYANG THERAPEUTICS CO LTD (CN) 2026-02-19 US disclosed
EP-4556466-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF Beyang Therapeutics Co., Ltd. (CN) 2025-05-21 EP disclosed
CN-119604488-A Protein tyrosine kinase inhibitor and medical application thereof 苏州必扬医药科技有限公司 2025-03-11 CN disclosed
WO-2024032584-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF 苏州必扬医药科技有限公司 2024-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049071-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF KDR, FLT1, ERBB2 L3MBTL1 607/4885ATM 723/4885HRH3 2004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.