Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308796 | 0.98 | EHMT2 (0.39) | HRH3HRH4ALOX15SIGMAR1EHMT2 | |
| SCHEMBL6305135 | 0.95 | ALDH1A1 (0.38) | HRH3HRH4ALOX15SIGMAR1EHMT2 | |
| SCHEMBL6533138 | 0.90 | ALOX15 (0.41) | HRH3ALOX15SIGMAR1CYP1A2CYP3A4 | |
| SCHEMBL6302885 | 0.88 | ALDH1A1 (0.40) | HRH3ALOX15SIGMAR1EHMT2EHMT1 | |
| SCHEMBL6304851 | 0.84 | ALDH1A1 (0.40) | HRH3ALOX15SIGMAR1EHMT2EHMT1 | |
| SCHEMBL6302848 | 0.84 | KDM1A (0.44) | HRH3SIGMAR1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL30786259 | 0.78 | L3MBTL1 (0.41) | HRH3HRH4SIGMAR1HRH1CYP1A2 | |
| SCHEMBL165242 | 0.77 | PARP1 (0.43) | HRH3HRH4CYP1A2CYP3A4MEN1 | |
| SCHEMBL6308791 | 0.75 | PARP1 (0.41) | HRH3HRH4CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL18235472 | 0.75 | LMNA (0.42) | SIGMAR1HRH1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949562-B2 | Heterocyclic compounds as ligands of the GABAA receptor | NEUROGEN CORPORATION (US) | 2005-09-27 | — | — | US | disclosed |