Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25031743 | 0.98 | SIGMAR1 (0.50) | SIGMAR1GNAI3GNAO1GNAI1CARM1 | |
| SCHEMBL1290862 | 0.91 | CARM1 (0.52) | SIGMAR1CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL17277591 | 0.86 | SIGMAR1 (0.42) | SIGMAR1GNAI3GNAO1GNAI1CARM1 | |
| SCHEMBL242420 | 0.82 | ALOX15 (0.57) | SIGMAR1GNAI3GNAO1GNAI1CARM1 | |
| SCHEMBL23828682 | 0.82 | CARM1 (0.60) | SIGMAR1CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL2953638 | 0.81 | GNAO1 (0.66) | SIGMAR1GNAI3GNAO1GNAI1CARM1 | |
| SCHEMBL10442393 | 0.81 | GNAO1 (0.66) | SIGMAR1GNAI3GNAO1GNAI1CARM1 | |
| SCHEMBL8322301 | 0.81 | GNAO1 (0.66) | SIGMAR1GNAI3GNAO1GNAI1CARM1 | |
| SCHEMBL8324109 | 0.81 | GNAO1 (0.66) | SIGMAR1GNAI3GNAO1GNAI1CARM1 | |
| SCHEMBL8321113 | 0.81 | GNAO1 (0.66) | SIGMAR1GNAI3GNAO1GNAI1CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023237015-A1 | N-TETRAZOLYL ARYL UREA DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | 杭州壹瑞医药科技有限公司 | 2023-12-14 | — | — | WO | disclosed |