Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18883021 | 1.00 | ENPP2 (0.43) | ENPP2TSHRCYP19A1TTRMEN1 | |
| SCHEMBL561018 | 0.82 | CYP19A1 (0.48) | TSHRCYP19A1TTRMEN1HTT | |
| SCHEMBL716259 | 0.82 | CYP19A1 (0.54) | TSHRCYP19A1TTRMEN1HTT | |
| SCHEMBL6330190 | 0.82 | CYP19A1 (0.54) | TSHRCYP19A1TTRMEN1HTT | |
| SCHEMBL3781044 | 0.76 | ENPP2 (0.60) | ENPP2TSHRKDM4E | |
| SCHEMBL30319435 | 0.76 | TSHR (0.56) | TSHRCYP19A1TTRMEN1HTT | |
| SCHEMBL12265205 | 0.76 | ALDH1A1 (0.47) | TSHRCYP19A1TTRMEN1HTT | |
| SCHEMBL31347504 | 0.76 | ACHE (0.54) | TSHRCYP19A1TTRMEN1HTT | |
| SCHEMBL11025268 | 0.76 | ACHE (0.54) | TSHRCYP19A1TTRMEN1HTT | |
| SCHEMBL18407603 | 0.76 | TSHR (0.56) | TSHRCYP19A1TTRMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486813-A | N-disubstituted phenyl acrylamide compound, and pharmaceutical composition and application thereof | 江南大学 | 2024-02-02 | — | — | CN | disclosed |