Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893519 | 1.00 | EGFR (0.46) | EGFRNOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL1896473 | 0.88 | EGFR (0.47) | EGFRKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL1893310 | 0.88 | KMT2A (0.47) | EGFRKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL1895466 | 0.86 | NMT1 (0.49) | EGFRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1889806 | 0.83 | MET (0.48) | — | |
| SCHEMBL1132184 | 0.83 | GAA (0.51) | EGFRKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18497845 | 0.83 | LMNA (0.50) | EGFRHPGDLMNAPLA2G2AFFAR4 | |
| SCHEMBL1895818 | 0.82 | FLT1 (0.46) | EGFR | |
| Hydrochloric Acid SCHEMBL1892857 | 0.82 | GAA (0.50) | EGFRKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18525720 | 0.81 | SYK (0.46) | EGFRKDM4EMCL1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924288-B | Quinolinyl-containing compound, pharmaceutical composition and application thereof | 北京普祺医药科技股份有限公司 | 2024-04-05 | — | — | CN | disclosed |