SCHEMBL30787602

SCHEMBL30787602

COC1CCN(CC=CC=O)CC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31029376 0.90 LTA4H (0.32)
SCHEMBL30787611 0.90 LTA4H (0.32)
SCHEMBL19720763 0.81 TRPA1 (0.33) TRPA1
SCHEMBL30787619 0.81 TRPA1 (0.33) TRPA1
SCHEMBL13895149 0.81 KCNQ3 (0.33) KDM4EALDH1A1
SCHEMBL21625324 0.76 KMT2A (0.34) KMT2AMEN1KDM4EALDH1A1TSHR
SCHEMBL27144799 0.76 HRH1 (0.36) KMT2AMEN1KDM4EALDH1A1TSHR
Hydrochloric Acid SCHEMBL30022400 0.75 HRH1 (0.35) KMT2AMEN1KDM4EALDH1A1TSHR
Hydrochloric Acid SCHEMBL27189838 0.75 HRH1 (0.35) KMT2AMEN1KDM4EALDH1A1TSHR
SCHEMBL20711677 0.73 KCNQ3 (0.34) KMT2AMEN1KDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4577549-A1 COMPOUNDS AND METHODS FOR MODULATING HER2 Iambic Therapeutics, Inc. (US) 2025-07-02 EP disclosed
WO-2024044570-A1 COMPOUNDS AND METHODS FOR MODULATING HER2 IAMBIC THERAPEUTICS, INC. (US) 2024-02-29 WO disclosed