SCHEMBL13895149

SCHEMBL13895149

COC1CCN(CC=O)CC1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KCNQ3 O43525 5/20 0.33
KCNQ2 O43526 5/20 0.33
OPRM1 P35372 1/20 0.32
OPRK1 P41145 1/20 0.32
LMNA P02545 2/20 0.32
AOC3 Q16853 1/20 0.31
LTA4H P09960 1/20 0.31
KCNQ4 P56696 1/20 0.31
KCNQ5 Q9NR82 1/20 0.31
TERT O14746 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5374788 0.88 LTA4H (0.34) AOC3LTA4H
SCHEMBL30787602 0.81 KMT2A (0.33) KDM4EALDH1A1
SCHEMBL2562675 0.80 CARM1 (0.33)
SCHEMBL2552557 0.80 LMNA (0.35) KCNQ3KCNQ2OPRM1OPRK1LMNA
SCHEMBL30433484 0.78
SCHEMBL8970839 0.76 BCHE (0.35) KCNQ3KCNQ2LMNA
SCHEMBL4319495 0.76 SMN1; SMN2 (0.37) KCNQ3KCNQ2LMNAAOC3KCNQ4
SCHEMBL2559725 0.76 CARM1 (0.48) ALDH1A1
SCHEMBL21625324 0.74 KMT2A (0.34) KCNQ3KCNQ2LMNAKCNQ4KCNQ5
SCHEMBL27144799 0.74 HRH1 (0.36) LMNATERTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
US-7524852-B2 Bicyclic pyrimidine derivatives KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-04-28 US disclosed