SCHEMBL30788358

SCHEMBL30788358

CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 16/20 0.47
▸ TFPI P10646 1/20 0.46
▸ RXFP1 Q9HBX9 1/20 0.45
▸ PTGS1 P23219 1/20 0.41
▸ GSTK1 Q9Y2Q3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29455880 0.88 TFPI (0.53) IL23RTFPIRXFP1
SCHEMBL29575493 0.87 TFPI (0.46) IL23RTFPIRXFP1
SCHEMBL29939729 0.87 TFPI (0.55) IL23RTFPIRXFP1
SCHEMBL31691755 0.86 NPY4R (0.44) PTGS1GSTK1
SCHEMBL30186434 0.85 IL23R (0.44) IL23RTFPIRXFP1
SCHEMBL30198545 0.84 TFPI (0.45) IL23RTFPIRXFP1
SCHEMBL30148472 0.84 TFPI (0.47) TFPIRXFP1
SCHEMBL30099637 0.84 TFPI (0.45) IL23RTFPI
SCHEMBL30942619 0.84 IL23R (0.48) IL23RTFPIRXFP1
SCHEMBL31047157 0.84 FOLH1 (0.48) TFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240076314-A1 PEPTIDE COMPOSITIONS AND METHODS FOR INHIBITING NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY GLO PHARMA, INC. 2024-03-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240076314-A1 PEPTIDE COMPOSITIONS AND METHODS FOR INHIBITING NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY CHRNB1, CHRNG, CHRNA1 IL23R 1502/4885TFPI 2394/4885RXFP1 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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