SCHEMBL29455880

SCHEMBL29455880

CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCC(=O)O)C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.53
▸ RXFP1 Q9HBX9 2/20 0.51
▸ IL23R Q5VWK5 9/20 0.49
▸ PTH1R Q03431 1/20 0.45
▸ KEAP1 Q14145 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29939729 0.96 TFPI (0.55) TFPIRXFP1IL23R
SCHEMBL29929055 0.92 TFPI (0.54) TFPIRXFP1PTH1RKEAP1
SCHEMBL29435830 0.92 TFPI (0.56) TFPIRXFP1PTH1R
SCHEMBL31182934 0.91 RXFP1 (0.58) TFPIRXFP1PTH1R
SCHEMBL30390186 0.91 RXFP1 (0.57) TFPIRXFP1PTH1R
SCHEMBL31343254 0.89 TFPI (0.53) TFPIRXFP1PTH1RKEAP1
SCHEMBL30168700 0.89 RXFP1 (0.51) TFPIRXFP1IL23RPTH1R
SCHEMBL31031482 0.89 NPY4R (0.51) TFPI
SCHEMBL30389981 0.88 RXFP1 (0.55) TFPIRXFP1PTH1RKEAP1
SCHEMBL30262134 0.88 TFPI (0.56) TFPIRXFP1PTH1RKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3915587-B1 IMPROVED CELL-TARGETING BINDING MOLECULE SAPREME TECH BV (NL) 2026-03-25 — — EP disclosed
US-20260000783-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECHNOLOGIES B.V. (NL) 2026-01-01 — — US disclosed
EP-4647436-A2 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES Sapreme Technologies B.V. (NL) 2025-11-12 — — EP disclosed
US-12453782-B2 Antibody-oligonucleotide conjugate SAPREME TECHNOLOGIES B.V. (NL) 2025-10-28 — — US disclosed
EP-3897735-B1 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES SAPREME TECH BV (NL) 2025-10-22 — — EP disclosed
US-20250302983-A1 Saponin Conjugates SAPREME TECHNOLOGIES B.V. (NL) 2025-10-02 — — US disclosed
EP-4588523-A2 IMPROVED CELL-TARGETING BINDING MOLECULE Sapreme Technologies B.V. (NL) 2025-07-23 — — EP disclosed
US-20250195682-A1 IMPROVED CELL-TARGETING BINDING MOLECULE SAPREME TECHNOLOGIES B.V. (NL) 2025-06-19 — — US disclosed
EP-4241847-B1 IMPROVED CELL-TARGETING BINDING MOLECULE SAPREME TECH BV (NL) 2025-06-04 — — EP disclosed
EP-4374927-A2 SAPONIN CONJUGATES Sapreme Technologies B.V. (NL) 2024-05-29 — — EP disclosed
EP-4223316-A2 IMPROVED ANTIBODY-OLIGONUCLEOTIDE CONJUGATE Sapreme Technologies B.V. (NL) 2023-08-09 — — EP disclosed
US-20230203153-A1 ANTIBODIES SPECIFIC TO ABCB5 AND USES THEREOF CHILDREN'S MEDICAL CENTER CORPORATION (US) 2023-06-29 — — US disclosed
US-20230173085-A1 Saponin Conjugates SAPREME TECHNOLOGIES B.V. (NL) 2023-06-08 — — US disclosed
EP-4015003-B1 IMPROVED ANTIBODY-OLIGONUCLEOTIDE CONJUGATE SAPREME TECH BV (NL) 2023-05-10 — — EP disclosed
CN-116096753-A Antibodies specific for ABCB5 and uses thereof 儿童医学中心公司 2023-05-09 — — CN disclosed
EP-4142793-A1 ANTIBODIES SPECIFIC TO ABCB5 AND USES THEREOF Children's Medical Center Corporation (US) 2023-03-08 — — EP disclosed
US-20220313834-A1 IMPROVED ANTIBODY-OLIGONUCLEOTIDE CONJUGATE SAPREME TECHNOLOGIES B.V. (NL) 2022-10-06 — — US disclosed
US-20220218837-A1 DRUG CONJUGATE SAPREME TECHNOLOGIES B.V. (NL) 2022-07-14 — — US disclosed
EP-4015003-A1 IMPROVED ANTIBODY-OLIGONUCLEOTIDE CONJUGATE SAPREME TECHNOLOGIES B.V. (NL) 2022-06-22 — — EP disclosed
US-20220111066-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECHNOLOGIES B.V. (NL) 2022-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220313834-A1 IMPROVED ANTIBODY-OLIGONUCLEOTIDE CONJUGATE CD40, TNFSF10, IGSF11 TFPI 2421/4885RXFP1 2059/4885IL23R 319/4885
US-20250302983-A1 Saponin Conjugates EPCAM, CD47, SHBG TFPI 2123/4885RXFP1 3659/4885IL23R 1068/4885
US-20230173085-A1 Saponin Conjugates EPCAM, CD47, SHBG TFPI 2123/4885RXFP1 3659/4885IL23R 1068/4885
US-20260000783-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW EPCAM, CD47, FCGR3B TFPI 1723/4885RXFP1 3267/4885IL23R 373/4885
US-20220111066-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW EPCAM, CD47, EGFR TFPI 1009/4885RXFP1 2944/4885IL23R 609/4885
US-20220218837-A1 DRUG CONJUGATE OSTC, ADCY7, ADCY3 TFPI 2481/4885RXFP1 3353/4885IL23R 1522/4885
US-20230203153-A1 ANTIBODIES SPECIFIC TO ABCB5 AND USES THEREOF ABCB4, ABCB7, ABCD3 TFPI 3907/4885RXFP1 4698/4885IL23R 3779/4885
US-12453782-B2 Antibody-oligonucleotide conjugate CD40, FCGR1A, TNFSF10 TFPI 2377/4885RXFP1 2114/4885IL23R 316/4885
US-20250195682-A1 IMPROVED CELL-TARGETING BINDING MOLECULE EPCAM, CD47, CD74 TFPI 2009/4885RXFP1 3789/4885IL23R 711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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