Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.38 |
| ▸ | HTR2B | P41595 | 7/20 | 0.38 |
| ▸ | HTR2A | P28223 | 6/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | IKZF1 | Q13422 | 3/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30790152 | 0.89 | PARP1 (0.40) | HTR2CHTR2BHTR2AKDRPARP1 | |
| SCHEMBL30789825 | 0.88 | KDR (0.39) | HTR2CHTR2BHTR2AKDRPARP1 | |
| SCHEMBL30789853 | 0.88 | DRD2 (0.44) | HTR2CHTR2BHTR2AKDRPARP1 | |
| SCHEMBL30790177 | 0.84 | HTR2C (0.38) | HTR2CHTR2BHTR2APARP1LMNA | |
| SCHEMBL30790468 | 0.81 | HTR2C (0.51) | HTR2CHTR2BHTR2APARP1CHRM2 | |
| SCHEMBL30459017 | 0.81 | HTR2C (0.46) | HTR2CHTR2BHTR2APARP1IKZF1 | |
| SCHEMBL31622545 | 0.80 | IKZF2 (0.53) | IKZF1IKZF2 | |
| SCHEMBL30459129 | 0.76 | HTR2B (0.44) | HTR2CHTR2BHTR2APARP1IKZF1 | |
| SCHEMBL30458379 | 0.76 | HTR2B (0.44) | HTR2CHTR2BHTR2APARP1IKZF1 | |
| SCHEMBL30459092 | 0.75 | HTR2C (0.47) | HTR2CHTR2BHTR2APARP1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032689-A1 | COMPOUND BASED ON ISOINDOLINE-SUBSTITUTED GLUTARIMIDE BACKBONE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-02-15 | — | — | WO | claimed |