Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GCG | P01275 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 2/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1111682 | 0.66 | HTR7 (0.56) | HTR7BCL2BAK1KDM4EALDH1A1 | |
| SCHEMBL1497158 | 0.65 | CYP2C19 (0.53) | HTR7CYP2C19GCGCYP1A2PTGDR2 | |
| SCHEMBL1559894 | 0.65 | CYP2C19 (0.49) | HTR7CYP2C19GCGCYP1A2PTGDR2 | |
| SCHEMBL16629574 | 0.65 | PPARA (0.46) | HTR7CYP2C19CYP1A2PTGDR2FFAR1 | |
| SCHEMBL1111757 | 0.64 | HTR7 (0.57) | HTR7BCL2BAK1KDM4EALDH1A1 | |
| SCHEMBL588394 | 0.64 | SIGMAR1 (0.67) | HTR7BCL2BAK1KDM4EALDH1A1 | |
| SCHEMBL18045052 | 0.64 | CYP1A2 (0.68) | CYP1A2MAP4K4PTGS2PTGS1KDM4E | |
| SCHEMBL1134842 | 0.64 | DPP4 (0.69) | HTR7CYP2C19CYP1A2FFAR1FFAR4 | |
| SCHEMBL1497090 | 0.64 | CYP2C19 (0.47) | HTR7CYP2C19GCGCYP1A2PTGDR2 | |
| SCHEMBL9652976 | 0.64 | CYP2C19 (0.47) | HTR7CYP2C19GCGBCL2BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032689-A1 | COMPOUND BASED ON ISOINDOLINE-SUBSTITUTED GLUTARIMIDE BACKBONE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-02-15 | — | — | WO | disclosed |