Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KIF5B | P33176 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23356054 | 1.00 | IKBKB (0.33) | IKBKBMEN1NPC1PKMRAB9A | |
| SCHEMBL23356033 | 0.78 | JAK2 (0.50) | MEN1NPC1RAB9AKMT2AGAA | |
| SCHEMBL30791243 | 0.78 | JAK2 (0.50) | MEN1NPC1RAB9AKMT2AGAA | |
| SCHEMBL30791228 | 0.76 | MAPT (0.44) | MEN1NPC1RAB9AKMT2AKDR | |
| SCHEMBL23356026 | 0.76 | MAPT (0.44) | MEN1NPC1RAB9AKMT2AKDR | |
| SCHEMBL23356027 | 0.76 | GRM4 (0.47) | KDRCHEK1FLT3PLK3GAA | |
| SCHEMBL30791242 | 0.76 | GRM4 (0.47) | KDRCHEK1FLT3PLK3GAA | |
| SCHEMBL23356041 | 0.73 | LMNA (0.41) | MEN1KMT2AKDRCHEK1FLT3 | |
| SCHEMBL23356011 | 0.73 | NUDT1 (0.43) | NPC1PKMRAB9AKMT2AMAPK1 | |
| SCHEMBL30791212 | 0.73 | LMNA (0.41) | MEN1KMT2AKDRCHEK1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313232-B | Novel heterocyclic derivatives | JW中外制药公司 | 2024-03-08 | — | — | CN | disclosed |