Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23356026 | 1.00 | MAPT (0.44) | MAPTRAPGEF4DHODHCHEK1FLT3 | |
| SCHEMBL23356009 | 0.89 | OPRM1 (0.38) | EGFRKDR | |
| SCHEMBL30791283 | 0.89 | OPRM1 (0.38) | EGFRKDR | |
| SCHEMBL30791212 | 0.88 | LMNA (0.41) | MAPTCHEK1FLT3PLK3KMT2A | |
| SCHEMBL23356011 | 0.88 | NUDT1 (0.43) | MAPTRAPGEF4RAB9AKMT2ANPC1 | |
| SCHEMBL30791220 | 0.88 | NUDT1 (0.43) | MAPTRAPGEF4RAB9AKMT2ANPC1 | |
| SCHEMBL23356041 | 0.88 | LMNA (0.41) | MAPTCHEK1FLT3PLK3KMT2A | |
| SCHEMBL23356027 | 0.88 | GRM4 (0.47) | CHEK1FLT3PLK3EGFRKDR | |
| SCHEMBL30791242 | 0.88 | GRM4 (0.47) | CHEK1FLT3PLK3EGFRKDR | |
| SCHEMBL23356137 | 0.84 | ZAP70 (0.36) | EGFRP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313232-B | Novel heterocyclic derivatives | JW中外制药公司 | 2024-03-08 | — | — | CN | disclosed |