SCHEMBL30792012

SCHEMBL30792012

CN[C@@H]1CCC[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPM1D O15297 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30473156 0.96 PPM1D (0.30) PPM1D
SCHEMBL11257498 0.81
SCHEMBL11260684 0.81
SCHEMBL10832135 0.79
SCHEMBL22075839 0.75 ALDH1A1 (0.35)
SCHEMBL9686714 0.74
SCHEMBL24677027 0.73 PPM1D (0.34) PPM1D
SCHEMBL12629186 0.73 PPM1D (0.34) PPM1D
SCHEMBL7464139 0.73 NPY1R (0.38) PPM1D
SCHEMBL5380476 0.73 NPY1R (0.38) PPM1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858865-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 CN disclosed