Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820283 | 0.85 | IDO1 (0.47) | HSD11B1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL27086306 | 0.85 | FNTA (0.40) | HSD11B1BRD4ALDH1A1LMNAGAA | |
| SCHEMBL30792272 | 0.84 | ALDH1A1 (0.49) | HSD11B1BRD4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL30792094 | 0.84 | HSD11B1 (0.40) | HSD11B1LMNAGAAFNTAFNTB | |
| SCHEMBL24819027 | 0.84 | HSD11B1 (0.40) | HSD11B1LMNAGAAFNTAFNTB | |
| SCHEMBL24818975 | 0.84 | EIF4EBP1 (0.48) | LMNAGAA | |
| SCHEMBL30792258 | 0.82 | ALDH1A1 (0.41) | HSD11B1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL24820727 | 0.82 | FNTA (0.39) | HSD11B1BRD4LMNAGAASMN1; SMN2 | |
| SCHEMBL30792055 | 0.82 | FNTA (0.39) | HSD11B1BRD4LMNAGAASMN1; SMN2 | |
| SCHEMBL24819024 | 0.81 | PARP10 (0.38) | HSD11B1LMNAGAAFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |