Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | EIF4E | P06730 | 4/20 | 0.47 |
| ▸ | DHODH | Q02127 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820734 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TP53CA1CA2HSD17B10 | |
| SCHEMBL24820600 | 0.85 | EIF4E (0.48) | ALDH1A1CA1CA2HSD17B10HPGD | |
| SCHEMBL30792061 | 0.85 | EIF4E (0.48) | ALDH1A1CA1CA2HSD17B10HPGD | |
| SCHEMBL24820314 | 0.82 | RAB9A (0.50) | ALDH1A1HSD17B10SMN1; SMN2TSHRDHODH | |
| SCHEMBL24820105 | 0.81 | EIF4E (0.50) | HSD17B10CASP1EIF4E | |
| SCHEMBL30792116 | 0.81 | EIF4E (0.50) | HSD17B10CASP1EIF4E | |
| SCHEMBL29193034 | 0.81 | SMN1; SMN2 (0.68) | ALDH1A1HSD17B10CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL6498907 | 0.81 | ALDH1A1 (0.61) | ALDH1A1TP53CA1CA2HSD17B10 | |
| SCHEMBL19514758 | 0.80 | ALDH1A1 (0.71) | ALDH1A1TP53CA1CA2HSD17B10 | |
| SCHEMBL4280740 | 0.79 | FOLH1 (0.59) | ALDH1A1TP53CA1CA2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117858707-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |