Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073012 | 1.00 | ALDH1A1 (0.78) | ALDH1A1POLBLMNAGAAKMT2A | |
| SCHEMBL16802983 | 1.00 | ALDH1A1 (0.78) | ALDH1A1POLBLMNAGAAKMT2A | |
| SCHEMBL12444230 | 0.91 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAGAAKMT2A | |
| SCHEMBL10047321 | 0.91 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAGAAKMT2A | |
| SCHEMBL12444212 | 0.91 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAGAAKMT2A | |
| SCHEMBL12516171 | 0.91 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAGAAKMT2A | |
| SCHEMBL10073008 | 0.91 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAGAAKMT2A | |
| SCHEMBL10047339 | 0.91 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAGAAKMT2A | |
| SCHEMBL10047332 | 0.91 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAGAAKMT2A | |
| SCHEMBL10073010 | 0.91 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2503984-B1 | SULFONIMINES AS BLEACHING ACTIVATORS | HENKEL AG & CO KGAA (DE) | 2017-11-08 | — | — | EP | disclosed |
| WO-2015086793-A1 | POLYMER SUPPORTED PHOSPHORIC ACIDS AND USE THEREOF AS CATALYSTS IN THE PREPARATION OF 3-INDOLYLMETHANAMINES | FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2015-06-18 | — | — | WO | disclosed |
| EP-2883879-A1 | Polymer supported phosphoric acids and use thereof as catalysts in the preparation of 3-indolylmethanamines | Fundació Institut Català d'Investigació Química (ES) | 2015-06-17 | — | — | EP | disclosed |
| US-8815935-B2 | Inhibitors of protein prenyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-26 | — | — | US | disclosed |
| US-20130102639-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-25 | — | — | US | disclosed |
| US-8093274-B2 | Inhibitors of protein prenyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093274-B2 | Inhibitors of protein prenyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-10 | — | — | US | disclosed |
| US-20110178138-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-07-21 | — | — | US | disclosed |
| US-20100063114-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-11 | — | — | US | disclosed |
| US-20100063114-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-11 | — | — | US | disclosed |
| WO-2010014054-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-04 | — | — | WO | disclosed |
| CN-101431996-A | Inhibitors of protein prenyltransferases | UNIV CALIFORNIA (US) | 2009-05-13 | — | — | CN | disclosed |
| EP-2007383-A2 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | The Regents of the University of California (US) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007111948-A2 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102639-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | RABGGTA, FNTA, RABGGTB | ALDH1A1 2160/4885POLB 3212/4885LMNA 3093/4885 |
| US-20100063114-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | GGT1, FNTA, FNTB | ALDH1A1 1074/4885POLB 2318/4885LMNA 2288/4885 |
| US-20110178138-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | RABGGTA, FNTA, RABGGTB | ALDH1A1 2160/4885POLB 3212/4885LMNA 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.