Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HRH2 | P25021 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797119 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP2C19TMEM97SIGMAR1HTR1A | |
| SCHEMBL30797014 | 0.88 | SMARCA2 (0.51) | HDAC1 | |
| SCHEMBL30797042 | 0.88 | SMARCA2 (0.51) | HDAC1 | |
| SCHEMBL29704310 | 0.83 | SMARCA2 (0.47) | SMN1; SMN2MAPT | |
| SCHEMBL23301307 | 0.83 | OPRM1 (0.43) | SMN1; SMN2CYP2C19TMEM97SIGMAR1HTR1A | |
| SCHEMBL29910532 | 0.83 | OPRM1 (0.43) | SMN1; SMN2CYP2C19TMEM97SIGMAR1HTR1A | |
| SCHEMBL30796426 | 0.83 | OPRM1 (0.43) | SMN1; SMN2CYP2C19TMEM97SIGMAR1HTR1A | |
| SCHEMBL30797146 | 0.83 | TRPC3 (0.43) | SMN1; SMN2CYP2C19GRIN2BNPC1RAB9A | |
| SCHEMBL30796943 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19TMEM97SIGMAR1HTR1A | |
| SCHEMBL23304195 | 0.82 | LTA4H (0.41) | SMN1; SMN2CYP2C19TMEM97SIGMAR1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539849-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |